Vitiligo is a chronic disease process. Its course is highly variable and unpredictable, but rapid onset followed by a period of stability or low progression is most characteristic. Up to 30% of vitiligo patients report some spontaneous repigmentation, particularly in sun-exposed areas, but this is almost never enough to be satisfactory to the patient
Treatment of vitiligo-associated disease (for example, thyroid disease) does not produce a return of pigment in areas discolored by vitiligo.